Effects of estrogen on transgender

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Skip navigation! Story from Trans America. Estrogen is an important part of many transgender women's transition process.

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Transgender hormone therapy of the male-to-female MTF type, also known as feminizing hormone therapyis hormone therapy and sex reassignment therapy to change the secondary sexual characteristics of transgender people from masculine or androgynous to feminine. Some intersex people also take this form of therapy, according to their personal needs and preferences. The purpose of the therapy is to cause the development of the secondary sex characteristics of the desired sexsuch as breasts and a feminine pattern of hairfatand muscle distribution.

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Transgender women are women whose recorded sex at birth was male but whose gender identity is female. Transfeminine people represent a group that includes not just transgender women but also non-binary people who have a more feminine gender identity than the one that is expected for their recorded sex at birth. Many transgender people experience what is known as gender dysphoria —this is discomfort caused by people's bodies not matching their sense of identity.

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Transitioning refers to any physical, mental, or emotional change that a person makes in order to better reflect their gender identity. Some transgender people identify as neither male nor female, or as a combination of male and female. Everyone—transgender or not—has a gender identity.

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Awareness and acceptance of transgenderism have grown exponentially in the last decade. Organizations vary in their preferred terminology for this phenomenon. The feeling that one really belongs to the opposite gender is also called gender dysphoria and gender incongruence.

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Transgender women on hormone therapy may be at a higher risk for cardiovascular problems, such as stroke, blood clots and heart attack, researchers reported Monday. The study was done by reviewing eight years of medical records of nearly 5, transgender patients in the Kaiser Health system, and looked at patients over the age of 18 who took hormones for gender transition. Over 97, cisgender patients — people whose sex assigned at birth matches their gender identity — with similar age and health characteristics were studied for comparison.

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In transgender women who have had their testes removed as part of the gender-affirming process, a form of estrogen called estradiol strengthens connections between areas of the brain involved in fine motor skills, learning, emotions and sensory perception, according a study to be presented Monday at ENDOthe Endocrine Society's annual meeting in New Orleans, La. These findings reflect changes on the brain that might have implications, for instance, for treating hot flashes and other symptoms in transgender women, the researchers say. Without any sex hormones, transgender women have the same symptoms, such as hot flashes, that postmenopausal women have, she said.

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When an individual is physically transitioning as a transgender woman, they are undergoing the process to transform biological male characteristics to ones similar to a biological female. Hormone replacement therapy is a process common among transgender people during transition to help create these changes. Hormone replacement therapy for trans women may include three different kinds of medicines: estrogen, testosterone blockers, and progesterone. Estrogen is the hormone responsible for most the appearance of female characteristics both physical and emotional.

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Gender-affirming treatment of transgender people requires a multidisciplinary approach in which endocrinologists play a crucial role. The aim of this paper is to review recent data on hormonal treatment of this population and its effect on physical, psychological, and mental health. The Endocrine Society guidelines for transgender women include estrogens in combination with androgen-lowering medications.

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In transgender men, or trans masculine people FTMthe most common medication used for transition is testosterone. Administration of testosterone via transdermal, intramuscular, subcutaneous, or oral routes lowers serum estradiol levels, raises serum testosterone levels, and results in the development of typical male secondary sex characteristics. Irreversible changes include: deepening of the voice, increase in facial and body hair growth, clitoral enlargement clitoromegalyand thickened facial bone structure. Some trans men also describe changes in emotions e.


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